Analytical Applications

Even the smallest imperfection can disrupt results in high-precision analytical instruments. Exceptional accuracy, repeatability, and leak-tight performance are crucial in this sector, because even the tiniest leak or pressure variation can compromise data quality and drive up costs.

At Clippard, we specialize in pressure and flow control solutions built to meet these exacting standards. Our EV Series valves, with proven ultra-low leak rates, are a cornerstone for this sector, and we offer specialized helium leak testing to meet the most stringent requirements of high-sensitivity instruments. Our Cordis electronic pressure controllers provide the stability and resolution needed to maintain precise, unwavering control over gas pressures and flows, ensuring consistent results time after time. And when off-the-shelf solutions aren’t enough, we work with your engineers to create customized components tailored to your specific needs.

Key advantages of our solutions include:

• Ultra-low leak rates for maximum system integrity
• Stable and precise pressure and flow control
• Proven repeatability for consistent analytical results
• Testing and certification options for the most demanding applications

DNA Mapping       

The challenge: DNA mapping systems require ultra-stable and repeatable fluid flow, but were compromised by general-purpose pressure controllers that lacked the necessary precision.

The solution: Clippard's Cordis CPC electronic pressure controllers use a closed-loop system to deliver extremely fine, stable control within thousandths of a psi.

The result: The system gained smooth, predictable, and repeatable fluid flow, allowing engineers to eliminate compensating hardware and focus on reliable scientific output.

Bio-reactors       

The challenge: Bioreactor manufacturers need highly precise and consistent control over gas mixtures (sparging) to optimize cell culture pH and dissolved oxygen for proliferation.

The solution: Clippard's DV series valves, installed on a custom manifold, deliver exceptional precision and repeatability for controlling O₂, CO₂, air, and N₂ gas flow.

The result: The system achieved better, more consistent control over critical cell growth parameters, significantly enhancing cell proliferation within the bioreactor.

Liquid Extraction       

The challenge: An OEM needed to reliably select between multiple solvents for vacuum distillation, requiring a low-leak solution with full media compatibility that could replace a cumbersome three-valve setup.

The solution: Clippard's NIV Series PTFE valves and custom PTFE manifolds provided inert and precise sealing, handling flows from 50 kPa vacuum to 30 psig.

The result: The solution simplified the system, replacing three valves per line with one, and minimized the size and overall cost for the customer while ensuring low-leak performance.

Gas Chromatography

The challenge: Gas chromatographs require exceptional pressure stability and high-resolution accuracy to ensure consistent flow rates for valid measurement and compound identification.

The solution: Precise pressure is controlled with our Cordis unit to a known and fixed orifice, ensuring stable flow through the column and injector valve, regardless of external fluctuations.

The result: Provides the stable, repeatable flow essential for accurate component speed measurement and reliable identification in laboratory gas chromatography.

Chemical Analysis

The challenge: Advanced chemical analysis systems require precise reagent mixing and flow control while handling aggressive fluids. Standard valves often suffer from high dead volume, reagent waste, and excessive heat buildup that can destabilize sensitive samples.

The solution:Clippard’s NIV Gradient Mixing Valves feature a unique diaphragm/poppet design for minimal dead volume. When paired with the Hit & Hold circuit, the valves provide full power for actuation before dropping to a lower "holding" current to minimize thermal transfer.

The result: The system achieves highly accurate, consistent mixing with significantly reduced heat generation. This protects reagent integrity, lowers power consumption, and extends valve life, ensuring reliable long-term performance in high-tech research labs.

Leak Testing

The challenge: Manufacturers of differential pressure decay leak testers need to automate operation and achieve faster, higher resolution, and more repeatable leak rate results.

The solution: Clippard's low-leak GV and MAV valves and its Cordis Electronic Pressure Regulator automate fast cycling and isolate pressure for high-resolution leak testing.

The result: These solutions optimize device speed and improves test quality, delivering automated, faster, and more repeatable, high-resolution leak rate measurements.